- Dance Companies, Ottumwa
- Day Spas, Ottumwa
- Decals, Ottumwa
- Decorating & Designing Services, Ottumwa
- Dehumidifying & Ventilating Equipment, Ottumwa - Suppliers & Wholesalers
- Delivery & Errand Services, Ottumwa
- Dentists, Ottumwa
- Dentures, Ottumwa
- Department Stores, Ottumwa
- Dermatologists, Ottumwa - Skin Doctors, Physicians & Surgeons (Dermatology)
- Dialysis Clinics, Ottumwa - Kidney Dialysis Centers
- Diamonds & Precious & Semi-Precious Stones, Ottumwa
- Diesel, Ottumwa - Engine Fuels, Oils & Lubricants
- Diesel Engine Repair & Service, Ottumwa
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- Disc Jockeys, Ottumwa
- Disciples Of Christ Church, Ottumwa
- Discount Stores, Ottumwa - Clothing, Grocery, Furniture, Etc
- Diving Services & Instruction, Ottumwa
- Divorce & Family Law Attorneys & Lawyers, Ottumwa
- Doctors, Physicians & Surgeons, Ottumwa
- Dogs, Ottumwa
- Door & Gate Operating Devices, Ottumwa
- Drinking Establishments, Ottumwa
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Ottumwa
- Dry Cleaning & Laundry, Ottumwa - Dry Cleaners
- Dryer Vent Cleaning, Repair & Installation, Ottumwa
- Drywall Contractors, Ottumwa - Drywall Repair & Installation Services
- Durable & Non Durable Goods & Products, Ottumwa
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